No DNA match from gloves found near Nancy Guthrie’s home, sheriff’s department says

Published: Feb. 17, 2026 at 11:36 AM PST|Updated: Feb. 17, 2026 at 6:03 PM PST

TUCSON, Ariz. (13 News/Gray News) - The Pima County Sheriff’s Department announced Tuesday that DNA from a set of gloves found near Nancy Guthrie’s home did not produce a match.

The negative result comes after DNA from gloves found approximately two miles from the 84-year-old’s Tucson-area home was tested through the CODIS database.

CODIS, the Combined DNA Index System, is a computer program that tracks state, local and national DNA profiles from convicted offenders, unsolved evidence from crime scenes and missing persons.

Investigators are now turning to commercial genealogical databases, like Ancestry.com, to search for familial matches to the glove DNA. That method has been used more and more when a DNA sample isn’t in the law enforcement databases.

One of the most famous incidents came with the 2018 arrest of the Golden State Killer, Joseph James DeAngelo. Investigators were able to trace DNA to DeAngelo because a relative of his had uploaded their DNA to one of the commercial genealogical databases.

Additional DNA evidence found at Nancy Guthrie’s home is still being analyzed, according to authorities. The DNA from the gloves is not the same as what was found at the property.

Investigators used blue-light technology to look for traces of DNA throughout the home.

Pima County Sheriff Chris Nanos said Monday that none of Nancy Guthrie’s family members are considered suspects in her disappearance.

“Not one single person in the family is a suspect,” Nanos told 13 News.

Nanos said Nancy Guthrie’s family has been “100% cooperative” and her close family members were ruled out as suspects “in the first few days.”

“We talked to them. We took their phones. We took their computers. We did everything. We processed their vehicles. We processed their homes. They have been really... they’re victims,” Nanos said.

Nancy Guthrie was reported missing from her home on Feb. 1 after she spent the previous night with her family.

The FBI increased the reward to $100,000.

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